Description
Product Characteristics: Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.,PLVAP,FELS,PV-1,PV1,gp68,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,PLVAP
Target Information: integral membrane protein associated with vesicles\, protein highly expressed in the caveolae in lung epithelium [RGD, Feb 2006]